Doxycycline Hyclate(24390-14-5)
Whakaahuatanga Hua
● Doxycycline Hcl he antibacterial spectrum he tino tata ki te Tetracycline me te Terramycin, engari he pai ake te painga, kia aro ki te Staphylococcus Aureus o te tetracycline-resistant, oxytetracycline, te wa roa.Ka whakamahia i te Senile Chronic Bronchitis, te mate o te manawa, mate pūkahukahu, tonsillitis whakapeka, mycoplasma pneumonia, mate urinary tract, paihana toto, koriri bacillary, lymphadenitis whakapeka, me etahi atu. He tino rongonui ki te turoro Nephropathy na te mea kaore e kitea he paihana mo te whatukuhu.
● Ko te Doxycycline Hyclate te momo tote hyclate o te doxycycline, he paturopi tetracycline tetracycline waihanga, whanui e whakaatu ana i te mahi paturopi.Ka herea te Doxycycline hyclate ki te 30S ribosomal subunit, pea ki te 50S ribosomal subunit, na reira ka aukati i te here o te aminoacyl-tRNA ki te mRNA-ribosomal complex.Ka arai tenei ki te aukati i te whakahiato pūmua.I tua atu, kua whakaatuhia e tenei kaihoko te aukati i te mahi collagenase.
Taupānga
Ka whakamahia te Doxycycline Hyclate ki te rongoa i te tini o nga mate huakita, tae atu ki era ka puta te hakihaki.Ka whakamahia ano te Doxycycline Hyclate hei aukati i te mate malaria.Ko te Doxycycline Hyclate e mohiotia ana he paturopi tetracycline.Ka mahi ma te aukati i te tipu o te huakita. Ko tenei paturopi he rongoa i nga mate huakita anake.
| Nga taonga | Whakatakotoranga | Hua |
| Te ahua | Te paura tioata kowhai | Ka rite |
| Tautuhinga | TLC | Ka rite |
| te tauhohenga waikawa pungatara ka puta he tae kowhai | Ka rite | |
| ka hoatu tauhohenga o te pūhaumāota | Ka rite | |
| PH | 2.0~3.0 | 2.3 |
| Te whakaurunga motuhake | i te 349nm e(1%) 300~355 | 320 |
| Te hurihanga whatu motuhake | -105 ~ -120° | -110° |
| Nga konganuku taumaha: | ≤50ppm | <20ppm |
| Ko nga poke-marama | i te 490nm ≤0.07 | 0.03 |
| Matū whai pānga | 6-epidoxycycline ≤2.0%metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) tetahi atu poke ≤0.5% karekau i kitea nga poke ≤0.1% (ep5) | 1.6%0.1% Kaore i kitea Kaore i kitea Kaore i kitea Kaore i kitea Kaore i kitea |
| Ewaro | 4.3~6.0% (m/m) | 4.5% |
| Te pungarehu ngongo | ≤0.4% | 0.05% |
| Wai | 1.4~2.8% | 1.8% |
| Te whakamatautau | 95.0~102.0% ( c22h25cln2o8) i runga i te matū waikore, waiwaro-kore | 98.6% |
| Whakamutunga | Kia rite ki te USP32 | |
