Amoxicillin Trihydrate (61336-70-7)
Whakaahuatanga
● Amoxicillin Trihydrate (61336-70-7)
● CAS Nama: 61336-70-7
● EINECS Nama:248-003-8
● MF: C16H19N3O5S
● Mōkī: 25kg / pahū
Nga Taipitopito Hua
Ko te Amoxicillin trihydrate, he penicillin-a-whanui-a-whaahanga-hangaia, he rite tonu te hihinga antibacterial, te painga me te tono ki te ampicillin.Ko te Amoxicillin trihydrate he hydrate ko te ahua trihydrate o te amoxicillin;he paturopi semisynthetic, ka whakamahia ko ia anake, ka whakakotahi ranei me te pāhare pāporo clavulanate (i raro i te ingoa hokohoko Augmentin) mo te maimoatanga o nga momo mate huakita.He mahi hei tarukino paturopi me te kaihoko antimicrobial.Kei roto he amoxicillin.Ko te Amoxicillin he momo paturopi aminopenicillin semisynthetic me te mahi huakita.Ka herea e te Amoxicillin me te whakakore i te pūmua here penicillin-binding (PBP) 1A kei runga i te kirikiri o roto o te pakitara o te pūtau huakita.Ko te whakakore i nga PBPs ka pokanoa ki te hononga-whakawhitinga o nga mekameka peptidoglycan e tika ana mo te kaha me te pakari o te pakitara o te pakitara huakita.Ka haukotia te whakahiatotanga o te pakitara huakita, ka hua te ngoikoretanga o te pakitara o te pūtau huakita me te lysis pūtau.
I kitea a Amoxicillin i te tau 1958, i whakamahia hei rongoa i te tau 1972. I whakaaetia a Amoxicillin mo te whakamahi rongoa i te United States i te tau 1974, me te United Kingdom i te tau 1977. Kei runga i te (WHO) World Health Organization's List of Essential Medicines.It Ko tetahi o nga rongoa paturopi e kiia ana mo nga tamariki.Kei te waatea te Amoxicillin hei rongoa whanui. I te tau 2020, ko te 40 te nuinga o nga rongoa rongoa i te United States, neke atu i te 15 miriona nga whakahaunga.
Taupānga
Ka whakamahia ki te rongoa i nga mate huakita, penei i te mate o te uma (tae atu ki te pneumonia) me te puku niho.Ka taea hoki te whakamahi tahi me etahi atu paturopi me nga rongoa hei rongoa i nga whewhe puku.He maha nga wa ka tohua mo nga tamariki, hei rongoa i nga mate taringa me nga mate o te uma.
| Nga kupu whakamatautau | Paerewa | Hua |
| Te whakamatautau | 95.0%~102.0% | 99.9% |
| PH | 3.5~5.5 | 4.6 |
| Te ahua o te otinga | 0.5mol/L HCL≤2# 2mol/L NH4 OH≤2# | 1#1# |
| Wai | 11.5%~14.5% | 13.2% |
| Matū whai pānga | poke (mōrahi)≤1.0% | 0.13% |
| Te hurihanga whatu motuhake | +290''~+315'' | +305° |
| Te pungarehu ngongo | ≤1.0% | 0.1% |
| NN-Dimethylannline | ≤20ppm | Kaore i whakamahia i roto i te hanga |
| Methylen pūhaumāota | ≤600ppm | 296ppm |
| Triethylamine | ≤320ppm | 155ppm |
| Acetone | ≤3000ppm | 95ppm |
| Whakamutunga: Ka tutuki ki te EP 6th Paerewa. | ||
